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Sharing science to understand Long COVID
RECOVER Research Review (R3) Seminar Series
The goal of the R3 Seminar Series is to share the RECOVER Initiative’s research findings with researchers and the public. These seminars accelerate scientific discovery by allowing experts to share their latest insights on Long COVID and related conditions. Some R3 sessions also inform the public about other research on Long COVID. You can find recordings of all R3 Seminar sessions in the Previous Seminars section below.
Ethical considerations for enrolling “invested parties” in large-scale clinical studies: Insights from the RECOVER Initiative
The speakers will discuss ethical considerations for enrolling individuals who have a direct role in the study – such as investigators, research staff, or patient, caregiver and community Representatives - as study participants. Drawing from experience with the RECOVER initiative, they will present an ethical framework for enrolling “invested parties” in research.
During the March 14th RECOVER Research Review (R3) Seminar, researchers presented on how to characterize PASC in adults using electronic health record (EHR) data. The seminar covered the RECOVER EHR cohort study, the National COVID Cohort Collaborative (N3C), and two different methods to identify PASC subphenotypes based on symptom presentation.
During the January 24th RECOVER Research Review (R3) Seminar, researchers presented on viral persistence and viral reservoirs in PASC. Presenters discussed current understandings of how the virus that causes COVID-19 can persist and form reservoirs in the body, leading to long-term effects.
During the January 10th RECOVER Research Review (R3) Seminar, researchers provided a high-level overview of the mechanistic pathways of PASC. Presenters covered immunology, pathology, and viral reservoirs, exploring how these factors contribute to long-term health issues following COVID-19 infection.
During the December 13th RECOVER Research Review (R3) Seminar, researchers presented on the vascular pathophysiology of PASC, exploring how blood vessel dysfunction might contribute to long-term effects following COVID-19 infection.
During the November 8th RECOVER Research Review (R3) Seminar, researchers presented their understanding of the biomarkers of PASC. Presenters discussed the need for biomarkers, early immunological findings, ultrasensitive viral antigen measurements, and markers of fungal translocation.
During the October 25th RECOVER Research Review (R3) Seminar, researchers presented on how symptoms following SARS-CoV-2 infection have been measured, the importance of understanding the scope of symptoms, and patient perception about the burden of various symptoms. Presenters discussed the development and validation of a symptom burden questionnaire, methods to assess symptoms among RECOVER adult cohort participants, and the development of a questionnaire to capture symptoms and their burdensomeness after COVID infection.
During the October 11th RECOVER Research Review (R3) Seminar, presenters discussed leveraging mobile health platform technologies to understand PASC. The seminar explored what is known about these technologies in PASC research, the gaps in our knowledge, and how RECOVER will contribute to filling these gaps.
During the September 27th RECOVER Research Review (R3) Seminar, researchers presented findings from autopsy studies on PASC. Presenters discussed what has been learned about PASC from autopsy studies, the gaps in our knowledge, and how RECOVER will contribute to filling these knowledge gaps.
During the September 13th RECOVER Research Review (R3) Seminar, researchers presented on the clinical spectrum of PASC with a focus on coagulopathies. Presenters discussed our current understanding of coagulopathies in PASC, the gaps in our knowledge, and how RECOVER will contribute to filling these knowledge gaps.
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