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Sharing science to understand Long COVID
RECOVER Research Review (R3) Seminar Series
The goal of the R3 Seminar Series is to share the RECOVER Initiative’s research findings with researchers and the public. These seminars accelerate scientific discovery by allowing experts to share their latest insights on Long COVID and related conditions. Some R3 sessions also inform the public about other research on Long COVID. You can find recordings of all R3 Seminar sessions in the Previous Seminars section below.
Understanding metformin use and Long COVID and ME/CFS following COVID-19 infection: Insights from two studies
RECOVER investigators will present findings about the association between metformin use and the incidence of Long COVID using the EHR-based cohort study. The speakers will also present findings about the incidence and prevalence of myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) following COVID-19 infection using the adult observational cohort study.
During the June 25th RECOVER Research Review (R3) Seminar, researchers presented details about RECOVER-SLEEP, which included two trials focused on identifying potential treatments for sleep disturbances. Researchers also shared details about RECOVER-ENERGIZE, which included one trial focused on potential treatments for exercise intolerance and one trial examining potential treatments for post-exertional malaise. All the trials were recruiting adults experiencing one or more of these symptoms after having COVID. The presentation also included updates on other RECOVER clinical trials in progress.
During the May 14th RECOVER Research Review (R3) Seminar, researchers presented findings from the RECOVER pregnancy observational cohort and EHR cohort about the association of SARS-CoV-2 infection during pregnancy and development of Long COVID.
During the April 23rd, RECOVER Research Review (R3) Seminar, the speakers discussed our current knowledge of Long COVID in children, including epidemiology and risk factors, symptoms, underlying mechanisms that cause symptoms, and functional outcomes.
During the March 19th RECOVER Research Review (R3) Seminar, research presented findings about vaccine effectiveness against Long COVID in children and the association between SARS-CoV-2 infection and symptoms and conditions in children and adults.
During the February 13th RECOVER Research Review (R3) Seminar, several pathobiology study awardees presented about the mechanisms of neurological (brain and nervous system) symptoms of Long COVID.
During the January 23rd RECOVER Research Review (R3) Seminar, researchers presented on the progress and future directions of the RECOVER Initiative. Speakers from the RECOVER adult, pediatric, and autopsy cohorts provided an overview of the progress to date, what is in the pipeline and the ultimate promise of RECOVER for each of the cohorts. A review of the current state of the science of Long COVID and gaps in knowledge was also discussed.
During the December 12th RECOVER Research Review (R3) Seminar, panelists discussed immune features of Long COVID, the relationship between Long COVID and metabolism (chemical reactions that provide the body with energy), and impact of acute and Long COVID on the brain.
During the November 14th RECOVER Research Review (R3) Seminar, researchers discussed multiple different biological mechanisms likely underlaid PASC manifestations. This seminar explored several prominent mechanisms that were areas of active study, including persistent SARS-CoV-2 viral reservoirs, abnormal immune system activation, and effects on metabolic pathways.
During the July 11th RECOVER Research Review (R3) Seminar, presenters discussed the disparities and environmental risk factors in PASC using EHR Insights. This seminar explored racial and ethnic disparities as well as community-level environmental factors in PASC among adults.
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