Sharing science to understand Long COVID

During the December 10th RECOVER Research Review (R3) Seminar, researchers described a recent pathobiology study investigating viral persistence, or when SARS-CoV-2 remains in a person’s body and continues to cause changes even after they recover from their initial sickness. The study’s findings suggest that viral persistence could be one reason why some people experience certain symptoms of Long COVID. View the recording on YouTube.

During the November 12th RECOVER Research Review (R3) Seminar, researchers described how they are studying people’s health and habits both before and during the pandemic to answer important questions about COVID-19 and its long-term effects. Specifically, two studies using data collected by the Collaborative Cohort of Cohorts for COVID-19 Research (C4R) have identified several different factors that could impact the protective effects of COVID-19 vaccines. View the recording on YouTube.

During the October 29th RECOVER Research Review (R3) Seminar, researchers highlighted patterns in electronic health record (EHR) data in patients who developed Long COVID after a first, or subsequent COVID-19 reinfection. By reviewing patient medical records from as early as March 2020, the findings from these studies provide insights into potential risks associated with developing Long COVID. View the recording on YouTube.

During the October 8th RECOVER Research Review (R3) Seminar, researchers described how RECOVER and the All of Us Research Program collaborate to advance our understanding of Long COVID. These different National Institutes of Health (NIH) initiatives are sharing health data and developing innovative tools to gain important insights from that data. View the recording on YouTube.

During the September 10th RECOVER Research Review (R3) Seminar, RECOVER researchers presented some early findings from the RECOVER Pediatric Observational Cohort study. They presented a symptom-based approach for identifying children and adolescents with Long COVID from a study published in JAMA. View the recording on YouTube.

During the June 25th RECOVER Research Review (R3) Seminar, researchers presented details about RECOVER-SLEEP, which included two trials focused on identifying potential treatments for sleep disturbances. Researchers also shared details about RECOVER-ENERGIZE, which included one trial focused on potential treatments for exercise intolerance and one trial examining potential treatments for post-exertional malaise. All the trials were recruiting adults experiencing one or more of these symptoms after having COVID. The presentation also included updates on other RECOVER clinical trials in progress. View the recording on YouTube.

During the May 14th RECOVER Research Review (R3) Seminar, researchers presented findings from the RECOVER pregnancy observational cohort and EHR cohort about the association of SARS-CoV-2 infection during pregnancy and development of Long COVID. View the recording on YouTube.

During the April 23rd, RECOVER Research Review (R3) Seminar, the speakers discussed our current knowledge of Long COVID in children, including epidemiology and risk factors, symptoms, underlying mechanisms that cause symptoms, and functional outcomes. View the recording on YouTube.

During the March 19th RECOVER Research Review (R3) Seminar, research presented findings about vaccine effectiveness against Long COVID in children and the association between SARS-CoV-2 infection and symptoms and conditions in children and adults. View the recording on YouTube.