Research

Making progress toward recovery

Together we can do more. The RECOVER Initiative brings together scientists, clinicians, patients and caregivers to understand recovery from the long-term effects of COVID.

Explore Research

How Research Works

Learn more about how RECOVER studies work, access RECOVER research protocols, and understand what to expect as a participant in RECOVER studies.

Community Participation

RECOVER includes community voices at all levels of the initiative, as we seek diverse experiences to inform our research.

Funding Opportunities

View current and previous RECOVER Funding Opportunities.

RECOVER Research Questions

What does recovery from COVID look like for different groups (like adults and children, or people of different races and ethnicities)?

How many people keep having health problems long after they get COVID?

How many people get new health problems after they get COVID?

What causes these health problems?

Why do some people get these health problems while others do not?

Does getting COVID trigger changes in the body that increase the risk of other conditions, such as long-term health problems affecting the lung, heart, or brain?

RECOVER Results

RECOVER Electronic Health Records (EHR) Study Compares Risks of Heart Problems after COVID Infection and mRNA COVID Vaccination

Researchers from RECOVER and the National Patient-Centered Clinical Research Network (PCORnet) compared the risk of heart problems after COVID infection and after mRNA COVID vaccination. They used EHR data from 40 health care systems representing more than 15 million people, aged 5 years or older. The study compared people of similar age, gender, and number of vaccine doses to see what increased the risk of heart problems.

The study found that the risk of heart problems after getting an mRNA COVID vaccine was very low for people of all ages and genders. Also, the risk of having heart problems after having COVID was significantly higher than after getting an mRNA COVID vaccine.

These findings support the continued use of the recommended mRNA COVID-19 vaccine for all eligible people aged 5 or older. See this recent study in the CDC’s Morbidity and Mortality Weekly Report (MMWR).

NIH
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April 1, 2022

RECOVER Together

Progress takes the best science.

The RECOVER Initiative will collect data from many patients across the country. This will include data from medical records to understand how people are experiencing Long COVID. Looking at what happens to patients over time can help us understand their Long COVID story. We will then combine these data to help answer big questions.

The detailed study plan—called the main protocols—is the same for all RECOVER studies. Using the same study plan lets us combine data from different study locations. This helps us get answers to important questions faster.

Also, each study brings specific kinds of information that will help us understand Long COVID. Various groups of people—known as cohorts—will be included in the studies. These include adults, children and their caregivers, and pregnant women and their newborn babies. This will help us understand how different people are experiencing Long COVID.

Interested in information about volunteering for RECOVER studies?
Sign up using this link.