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Sharing science to understand Long COVID

RECOVER Research Review (R3) Seminar Series

The goal of the R3 Seminar Series is to share the RECOVER Initiative’s research findings with researchers and the public. These seminars accelerate scientific discovery by allowing experts to share their latest insights on Long COVID and related conditions. Some R3 sessions also inform the public about other research on Long COVID. You can find recordings of all R3 Seminar sessions in the Previous Seminars section below.

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upcoming R3 Seminars

Upcoming Seminars

December 10, 2024

Persistent SARS-CoV-2 antigens and correlation with Long COVID symptoms: Findings from a multi-cohort study

Source: NIH

Check back for upcoming seminars!

Previous Seminars

• Source: NIH

Vaccine response and time to recovery from COVID-19 in a multi-cohort collaborative (C4R)

  • Elizabeth C. Oelsner, MD, DrPH, Columbia University Irving Medical Center
  • John Kim, MD, University of Virginia
  • Wendy Post, MD, MS, Johns Hopkins University
Watch Recording External link

• Source: NIH

Patterns of PASC with Initial COVID-19 Infections and Reinfections: EHR Insights

  • Richard Moffitt, PhD, Emory University School of Medicine
  • Emily Hadley, MS, RTI International
  • Hannah Mandel, MS, NYU Langone Health
  • Ravi Jhaveri, MD, Ann & Robert H. Lurie Children's Hospital of Chicago; Northwestern University Feinberg School of Medicine
Watch Recording External link

Audio transcript (PDF, 244 KB)

• Source: NIH

Advancing Long COVID Research by Fostering Collaboration between RECOVER and the All of Us Research Program

  • Hiral Master, PT, PhD, MPH, Vanderbilt University Medical Center
  • Emily Pfaff, PhD, MS, University of North Carolina School of Medicine
  • Chris Lunt, Chief Technology Officer, All of Us Research Program, NIH
Watch Recording External link

Audio transcript (PDF, 256 KB)

• Source: NIH

Characterization of Long COVID Among Children and Adolescents, Cohort Insights

  • Melissa Stockwell, MD, MPH, Columbia University; New York-Presbyterian Hospital
  • Rachel S. Gross, MD, MS, New York University School of Medicine
  • Tanayott Thaweethai, PhD, Massachusetts General Hospital; Harvard Medical School
  • Andrea S. Foulkes, ScD, Massachusetts General Hospital; Harvard Medical School
  • Megan Carmilani, RECOVER Representative; Founder and President of Long COVID Families
Watch Recording External link

Audio transcript (PDF, 226 KB)

• Source: NIH

RECOVER-SLEEP and RECOVER-ENERGIZE – Clinical Trials for Sleep Disturbances, Exercise Intolerance, and Post Exertional Malaise Due to Long COVID

  • Christina Barkauskas, MD, Duke University School of Medicine
  • Susan Redline, MD, MPH, Harvard Medical School; Brigham and Women’s Hospital
  • Lucinda Bateman, MD, Bateman Horne Center
  • Janna Friedly, MD, MPH, University of Washington
  • G. Michael Felker, MD, MHS, Duke University
  • Barry Make, MD, National Jewish Health
  • Sonya Sutton, Duke University
Watch Recording External link

Audio transcript (PDF, 222 KB)
Responses to participants' questions (PDF, 286 KB)

• Source: NIH

SARS-CoV-2 infection during pregnancy and development of Long COVID

  • Ann M. Bruno, MD, University of Utah
  • Torri Metz, MD, MS, University of Utah
  • Chengxi Zang, PhD, Weill Cornell Medicine, Cornell University
  • Valerie Flaherman, MD, MPH, University of California, San Francisco
Watch Recording External link

Audio transcript (PDF, 265 KB)
Responses to participants' questions (PDF, 236 KB)

• Source: NIH

PASC in Children: State of the Science and Future Directions

  • Suchitra Rao, MBBS, MSCS, Children’s Hospital Colorado; University of Colorado
  • Abigail Case, MD, Children’s Hospital of Philadelphia; University of Pennsylvania
  • Rebecca Letts, BA, RECOVER Representative
  • Melissa Stockwell, MD, MPH, Columbia University; New York-Presbyterian Hospital
Watch Recording External link

Audio transcript (PDF, 244 KB)
Responses to participants' questions (PDF, 238 KB)

• Source: NIH

Patterns and Prevention of Long COVID: Findings from RECOVER EHR Cohort Studies

  • Yongkang Zhang, PhD, Weill Cornell Medicine
  • Hanieh Razzaghi, PhD, MPH, Children’s Hospital of Philadelphia
  • Ravi Jhaveri, MD, Ann & Robert H. Lurie Children's Hospital of Chicago; Northwestern University
Watch Recording External link

Audio transcript (PDF, 380 KB)
Responses to participants' questions (PDF, 250 KB)

• Source: NIH

Understanding Neurological Manifestations of PASC and Cerebral Vascular Injury

  • Serena Spudich, MD, MA, Yale School of Medicine
  • Igor J. Koralnik, MD, Northwestern University
  • Shibani S. Mukerji, MD, PhD, Massachusetts General Hospital; Harvard Medical School
  • Jeymohan Joseph, PhD, National Institute of Mental Health, NIH
Watch Recording External link

Audio transcript (PDF, 233 KB)
Responses to participants' questions (PDF, 207 KB)

• Source: NIH

RECOVER Observational Studies Consortium: Where we are and where we are headed

  • Igho Ofotokun, MD, MSc, (Adult Cohort Coordinating Committee Chair), Emory University School of Medicine
  • Melissa Stockwell, MD, MPH, (Pediatric Cohort Coordinating Committee Chair), Columbia University; New York-Presbyterian Hospital
  • James Stone, MD, PhD, (Autopsy Cohort Coordinating Committee Chair), Massachusetts General Hospital; Harvard Medical School
  • Brittany D. Taylor, MPH, (RECOVER National Community Engagement Group (NCEG) Co-Chair), American Heart Association
Watch Recording External link

Audio transcript (PDF, 351 KB)
Responses to participants' questions (PDF, 195 KB)

• Source: NIH

Impacts of SARS-CoV-2 infection on brain, immunity, and metabolism

  • Catherine Blish, MD, PhD, Stanford University School of Medicine
  • Cliff Rosen, MD, MaineHealth Institute for Research, Tufts University
  • Avindra Nath, MD, National Institute of Neurological Disorders and Stroke at NIH
  • Sudha Seshadri, MD, University of Texas Health Sciences Center San Antonio
Watch Recording External link

Audio transcript (PDF, 218 KB)
Responses to participants' questions (PDF, 224 KB)

• Source: NIH

Understanding the role of the immune system in PASC

  • Timothy Henrich, MD, University of California San Francisco
  • Andrea Cox, MD, PhD, Johns Hopkins University
  • Akiko Iwasaki, PhD, Yale School of Medicine
  • PJ Utz, MD, Stanford University
Watch Recording External link

Audio transcript (PDF, 279 KB)
Responses to participants' questions (PDF, 289 KB)

• Source: NIH

RECOVER in Action: Disparities and Environmental Risk Factors in PASC, EHR Insights

  • Thomas Carton, PhD, MS, Louisiana Public Health Institute
  • Yongkang Zhang, PhD, Weill Cornell Medicine
  • Gelise Thomas, JD, MS, Case Western Reserve University
Watch Recording External link

Audio transcript (PDF, 352 KB)
Responses to participants' questions (PDF, 305 KB)

• Source: NIH

RECOVER in Action: Characterization of PASC Among Adults, Cohort Insights

  • Andrea S. Foulkes, ScD, Massachusetts General Hospital; Harvard Medical School
  • Tanayott Thaweethai, PhD, Massachusetts General Hospital; Harvard Medical School
  • Sairam Parthasarathy, MD, University of Arizona
  • Upinder Singh, MD, Stanford University School of Medicine
Watch Recording External link

Audio transcript (PDF, 250 KB)
Responses to participants' questions (PDF, 269 KB)

• Source: NIH

RECOVER in Action: PASC in Children and Adolescents, EHR Insights

  • Vitaly Lorman, PhD, Children’s Hospital of Philadelphia
  • Suchitra Rao, MBBS, MSCS, Children’s Hospital Colorado; University of Colorado
  • Kelan Tantisira, MD, MPH, University of California San Diego; Rady Children's Hospital
Watch Recording External link

Audio transcript (PDF, 242 KB)
Responses to participants' questions (PDF, 303 KB)

• Source: NIH

RECOVER in Action: Status of Clinical Trial Protocols

  • Kanecia Zimmerman, MD, PhD, MPH, Principal Investigator for the RECOVER Clinical Trials Data Coordinating Center, Duke Clinical Research Institute
  • Renee Leverty, BSN, MA, Associate Director Research Together, Duke Clinical Research Institute
  • Christine Maughan, BS, Patient Representative
  • Marta Cerda, JD, Patient Representative
Watch Recording External link

Audio transcript (PDF, 262 KB)
Responses to participants' questions (PDF, 251 KB)

• Source: NIH

Mechanistic Pathways of PASC Session 3: Organ Damage and Reprogramming of Host Tissues and Organs

  • Benjamin tenOever, PhD, NYU Grossman School of Medicine
  • Douglas D. Fraser, MD, PhD, Western University
  • James R. Heath, PhD, Institute for Systems Biology
  • Jim Stone, MD, PhD, Massachusetts General Hospital, Harvard Medical School
Watch Recording External link

Audio transcript (PDF, 310 KB)
Responses to participants' questions (PDF, 213 KB)

• Source: NIH

RECOVER in Action: Characterization of PASC Among Adults, EHR Insights

  • Thomas Carton, PhD, MS, Louisiana Public Health Institute
  • Emily Pfaff, PhD, MS, University of North Carolina Chapel Hill School of Medicine
  • Melissa Haendel, PhD, FACMI, University of Colorado Anschutz Medical Campus
  • Fei Wang, PhD, FACMI, FAMIA, FIAHSI, Weill Cornell Medicine
  • Megan Fitzgerald, PhD, Patient Led Research Collaborative
Watch Recording External link

Audio transcript (PDF, 217 KB)
Responses to participants' questions (PDF, 240 KB)

• Source: NIH

Mechanistic Pathways of PASC Session 2: Viral Persistence and Viral Reservoirs

  • Tim Henrich, MD, University of California, San Francisco
  • Sindhu Mohondas, MD, University of Southern California; Children's Hospital of Los Angeles
  • Mehul Suthar, PhD, Emory University
  • Adolfo Garcia-Sastre, PhD, Icahn School of Medicine at Mount Sinai
Watch Recording External link

Audio transcript (PDF, 335 KB)
Responses to participants' questions (PDF, 181 KB)

• Source: NIH

Mechanistic Pathways of PASC Session 1: Overview of Mechanistic Pathways

  • Akiko Iwasaki, PhD, Yale School of Medicine
  • Jim Stone, MD, PhD, Massachusetts General Hospital
  • Amy Proal, PhD, PolyBio Research Foundation
  • Marrah Lachowicz-Scroggins, PhD, National Institutes of Health, National Heart, Lung, and Blood Institute (NHLBI)
Watch Recording External link

Audio transcript (PDF, 246 KB)
Responses to participants' questions (PDF, 284 KB)

• Source: NIH

Vascular Pathophysiology of PASC

  • Joel Trinity, PhD, University of Utah
  • Katelyn Ludwig, PhD, University of Colorado
  • Naomi Hamburg, MD, MS, Boston Medical Center
  • Discussant: Janet Mullington, PhD, Harvard Medical School; Beth Israel Deaconess Medical Center
Watch Recording External link

Audio transcript (PDF, 233 KB)
Responses to participants' questions (PDF, 217 KB)

• Source: NIH

Understanding the Biomarkers of PASC

  • Michael Peluso, MD, University of California, San Francisco
  • Mohamed Abdel-Mohsen, PhD, The Wistar Institute
  • David R. Walt, PhD, Harvard Medical School; Brigham and Women's Hospital
  • Grace McComsey, MD, University Hospitals Health System; Case Western Reserve University
Watch Recording External link

Audio transcript (PDF, 236 KB)
Responses to participants' questions (PDF, 228 KB)

• Source: NIH

Frequency and Burden of Symptoms Following SARS-CoV-2 Infection

  • Nedra Whitehead, PhD, RTI International
  • Sarah Hughes, PhD, University of Birmingham
  • Sharon Saydah, PhD, MHS, Centers for Disease Control and Prevention
  • Leora Horwitz, MD, NYU Langone Health
Watch Recording External link

Audio transcript (PDF, 244 KB)
Responses to participants' questions (PDF, 256 KB)

• Source: NIH

Leveraging Mobile Health Platform Technologies to Understand PASC

  • Jennifer Radin, PhD, MPH, Scripps Research Translational Institute
  • Vik Kheterpal, MD, CareEvolution
  • Arjun Venkatesh, MD, MBA, MHS, Yale School of Medicine
  • Erica Spatz, MD, MHS, Yale School of Medicine
  • Andrew Weitz, PhD, National Institute of Biomedical Imaging and Bioengineering
Watch Recording External link

Audio transcript (PDF, 237 KB)
Responses to participants' questions (PDF, 234 KB)

• Source: NIH

SARS-CoV-2 Infection: Findings from Autopsy Studies

  • Stephanie Haasnoot, Icahn School of Medicine at Mount Sinai Hospital
  • Marie-Abele Bind, PhD, Massachusetts General Hospital
  • Lauren Decker, MD, New Mexico Office of the Medical Investigator
  • James Stone, MD, PhD, Massachusetts General Hospital; Harvard Medical School
Watch Recording External link

Audio transcript (PDF, 229 KB)
Responses to participants' questions (PDF, 231 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Coagulopathies

  • Jean Connors, MD, Brigham and Women's Hospital; Harvard Medical School
  • Resia Pretorius, PhD, Stellenbosch University
  • Jeffrey S. Berger, MD, MS, FAHA, FACC, NYU Langone School of Medicine
  • Shari Brosnahan, MD, NYU Langone School of Medicine
Watch Recording External link

Audio transcript (PDF, 232 KB)
Responses to participants' questions (PDF, 198 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Sleep

  • Sairam Parthasarathy, MD, University of Arizona
  • Susan Redline, MD, MPH, Harvard Medical School; Harvard TH Chan School of Public Health; Brigham and Women's Hospital
  • Monika Haack, PhD, Harvard Medical School; Beth Israel Deaconess Medical Center
  • Janet Mullington, PhD, Harvard Medical School; Beth Israel Deaconess Medical Center
Watch Recording External link

Audio transcript (PDF, 224 KB)
Responses to participants' questions (PDF, 179 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Mental Health

  • Richard Gallagher, PhD, NYU Langone Health
  • Roy Perlis, MD, MSc, Massachusetts General Hospital
  • Doug Bremner, MD, Emory University School of Medicine
  • Naomi Simon, MD, MSc, NYU Langone Health
Watch Recording External link

Audio transcript (PDF, 238 KB)
Responses to participants' questions (PDF, 308 KB)

• Source: NIH

Clinical Spectrum of PASC: Sex Differences in PASC

  • Andrea Edlow, MD, MSc, Massachusetts General Hospital; Harvard Medical School
  • Vanessa Jacoby, MD, MAS, University of California San Francisco
  • Jim Hotaling, MD, MS, FECSM, University of Utah
  • Torri Metz, MD, MS, University of Utah
Watch Recording External link

Audio transcript (PDF, 229 KB)
Responses to participants' questions (PDF, 220 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Metabolism and Gastrointestinal Function

  • Clifford Rosen, MD, Tufts University School of Medicine; Maine Medical Center's Research Institute
  • Emily Gallagher, MD, PhD, Icahn School of Medicine at Mount Sinai
  • Jane Reusch, MD, University of Colorado Anschutz Medical Campus
  • Lucio Miele, MD, PhD, Louisiana State University Health Sciences Center
  • Philipp Scherer, PhD, Touchstone Diabetes Center; University of Texas Southwestern Medical Center
Watch Recording External link

Audio transcript (PDF, 233 KB)
Responses to participants' questions (PDF, 250 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Cardio-Pulmonary Function

  • Jennifer Su, MD, Children's Hospital Los Angeles; University of Southern California
  • Aloke Finn, MD, CVPath Institute Inc; University of Maryland
  • Matt Oster, MD, MPH, Children's CORPS (Cardiac Outcomes Research Program at Sibley Heart Center); Children's Healthcare of Atlanta; Emory University
  • Anu Lala, MD, The Mount Sinai Hospital; Icahn School of Medicine at Mount Sinai
  • Erika Berman Rosenzweig, MD, Columbia University Medical Center/New York-Presbyterian Hospital
Watch Recording External link

Audio transcript (PDF, 237 KB)
Responses to participants' questions (PDF, 172 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Neuro-cognitive Function

  • Melissa Cortez, DO, University of Utah Hospitals and Clinics
  • Alejandra González-Duarte, MD, PhD, NYU Langone Health
  • Sudha Seshadri, MD, University of Texas Health Sciences Center at San Antonio
  • Richard Gallagher, PhD, NYU Langone Health
  • Jennifer A. Frontera, MD, NYU Langone Health
Watch Recording External link

Audio transcript (PDF, 235 KB)
Responses to participants' questions (PDF, 204 KB)

• Source: NIH

Leveraging EHR/Real World Data to Understand PASC

  • Melissa Haendel, PhD, University of Colorado Anschutz Medical Campus
  • Thomas Carton, PhD, MS, Louisiana Public Health Institute
  • Christopher Chute, MD, DrPH, Johns Hopkins University
  • Rainu Kaushal, MD, MPH, Weill Cornell Medicine; New York-Presbyterian Hospital
  • Josh Fessel, MD, PhD, National Center for Advancing Translational Sciences, National Institutes of Health
  • Rachel Hess, MD, MS, Spencer Fox Eccles School of Medicine at the University of Utah
Watch Recording External link

Audio transcript (PDF, 222 KB)
Responses to participants' questions (PDF, 269 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Dysautonomia

  • Mitchell Miglis, MD, Department of Neurology and Neurological Sciences, Stanford University
  • Tae Chung, MD, Johns Hopkins University
  • Lauren Stiles, JD, Dysautonomia International, Stony Brook University Renaissance School of Medicine
  • Satish Raj, MD MSCI, University of Calgary
  • Peter Novak, MD, PhD, Autonomic Laboratory, Brigham and Women's Faulkner Hospital, Harvard Medical School
Watch Recording External link

Audio transcript (PDF, 248 KB)
Responses to participants' questions (PDF, 228 KB)

• Source: NIH

Clinical Spectrum of PASC: Focus on Pediatrics, including MIS-C

  • Tellen D. Bennett, MD, MS, University of Colorado School of Medicine, Children’s Hospital Colorado
  • Gail D. Pearson, MD, ScD, Division of Cardiovascular Sciences at the National Heart, Lung, and Blood Institute, National Institutes of Health
  • Ravi Jhaveri, MD, FPIDS, FAAP, Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University Feinberg School of Medicine
  • Josh Fessel, MD, PhD, National Center for Advancing Translational Sciences, National Institutes of Health
  • Ericka L. Fink, MD, MS, UPMC Children's Hospital of Pittsburgh
Watch Recording External link

Audio transcript (PDF, 230 KB)
Responses to participants' questions (PDF, 272 KB)

• Source: NIH

Commonalities with Other Disorders and Post-viral Syndromes: Focus on ME/CFS

  • Nancy Klimas, MD, Director, Institute for Neuro-Immune Medicine, Nova Southeastern University, Miami VAMC GRECC
  • Anthony Komaroff, MD, Simcox-Clifford-Higby Professor of Medicine, Harvard Medical School, Senior Physician, Brigham and Women’s Hospital
  • Benjamin Natelson, MD, Director, Pain & Fatigue Study Center, Professor of Neurology, Icahn School of Medicine at Mount Sinai
  • David Systrom, MD, Assistant Professor of Medicine, Harvard Medical School, Brigham and Women’s Hospital
Watch Recording External link

Audio transcript (PDF, 226 KB)
Responses to participants' questions (PDF, 314 KB)

• Source: NIH

Clinical Spectrum of PASC: Overview

  • Hannah Davis, Co-Founder, Patient-Led Research Collaborative
  • Benard P. Dreyer, MD, FAAP, Professor of Pediatrics, NYU School of Medicine
  • Sindhu Mohandas, MD, Assistant Professor of Pediatrics, Infectious Diseases, Children’s Hospital Los Angeles, University of Southern California
  • Igho Ofotokun, MD, MSc, Professor of Medicine, Emory University
Watch Recording External link

Audio transcript (PDF, 186 KB)
Responses to participants' questions (PDF, 189 KB)

• Source: NIH

Epidemiology of Post-Acute Sequelae of SARS-CoV-2 Infection: Current Understanding and Key Questions

  • Sharon Saydah, PhD, Senior Scientist, Respiratory Viruses Branch, Division of Viral Diseases, Centers for Disease Control and Prevention
  • Elizabeth (Beth) Unger, MD, PhD, Chief, Chronic Viral Disease Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention
  • Steven G. Deeks, MD, Professor of Medicine in Residence, School of Medicine, University of California San Francisco; faculty, Division of HIV, Infectious Diseases and Global Medicine, Zuckerberg San Francisco General Hospital
  • Valerie Flaherman, MD, MPH, Professor of Pediatrics and Epidemiology and Biostatistics University of California, San Francisco
Watch Recording External link

Audio transcript (PDF, 178 KB)
Responses to participants' questions (PDF, 237 KB)

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