Can multisystem inflammatory syndrome in children be managed in the outpatient setting? An EHR-based cohort study from the RECOVER Program

Jhaveri, R; Webb, R; Razzaghi, H; et al., Journal of the Pediatric Infectious Disease Society

Published

April 2023

Journal

Journal of the Pediatric Infectious Disease Society

Abstract

Using electronic health record data combined with primary chart review, we identified seven children across nine participant pediatric medical centers with a diagnosis of Multisystem Inflammatory Syndrome in Children (MIS-C) managed exclusively as outpatients. These findings should raise awareness of mild presentations of MIS-C and the option of outpatient management.

Authors

Ravi Jhaveri, Ryan Webb, Hanieh Razzaghi, Julia Schuchard, Asuncion Mejias, Tellen D Bennett, Pei-Ni Jone, Deepika Thacker, Grant S Schulert, Colin Rogerson, Jonathan D Cogen, L Charles Bailey, Christopher B Forrest, Grace M Lee, Suchitra Rao; RECOVER consortium

Keywords

COVID; inflammatory; multisystem; outpatients; syndromes

Short Summary

RECOVER researchers explored Multisystem Inflammatory Syndrome in Children (MIS-C), a Long COVID symptom where there is inflammation (swelling) of multiple organ systems. Researchers looked to see if MIS-C can be identified and managed in the home (outpatient) instead of in the hospital (inpatient).

An organ system is a collection of organs in your body dedicated to maintaining necessary functions. For example, your heart, arteries, and veins make up the Cardiovascular System--the system responsible for maintaining blood flow and delivering oxygen throughout the body.

Researchers were able to identify that in some patients, their MIS-C symptoms were mild enough to be treated at home and not require hospitalization. These results raise awareness that MIS-C can present in milder forms with the option to treat it at home if directed by a physician.