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Can multisystem inflammatory syndrome in children be managed in the outpatient setting? An EHR-based cohort study from the RECOVER Program

Jhaveri, R; Webb, R; Razzaghi, H; et al., Journal of the Pediatric Infectious Disease Society, April 2023

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Short Summary

RECOVER researchers explored Multisystem Inflammatory Syndrome in Children (MIS-C), a Long COVID symptom where there is inflammation (swelling) of multiple organ systems. Researchers looked to see if MIS-C can be identified and managed in the home (outpatient) instead of in the hospital (inpatient). 

An organ system is a collection of organs in your body dedicated to maintaining necessary functions. For example, your heart, arteries, and veins make up the Cardiovascular System--the system responsible for maintaining blood flow and delivering oxygen throughout the body.

Researchers were able to identify that in some patients, their MIS-C symptoms were mild enough to be treated at home and not require hospitalization. These results raise awareness that MIS-C can present in milder forms with the option to treat it at home if directed by a physician.

This summary was prepared by the RECOVER Initiative.

Publication Details

DOI: 10.1093/jpids/piac133

Abstract

Using electronic health record data combined with primary chart review, we identified seven children across nine participant pediatric medical centers with a diagnosis of Multisystem Inflammatory Syndrome in Children (MIS-C) managed exclusively as outpatients. These findings should raise awareness of mild presentations of MIS-C and the option of outpatient management.

Authors

Ravi Jhaveri, Ryan Webb, Hanieh Razzaghi, Julia Schuchard, Asuncion Mejias, Tellen D Bennett, Pei-Ni Jone, Deepika Thacker, Grant S Schulert, Colin Rogerson, Jonathan D Cogen, L Charles Bailey, Christopher B Forrest, Grace M Lee, Suchitra Rao, RECOVER consortium

Keywords

COVID; inflammatory; multisystem; outpatients; syndromes

Tags

Study Type
  • Electronic Health Record (EHR)
Participants
  • Pediatric
Findings
  • New-onset and Pre-existing Conditions