Post-acute sequelae of SARS-CoV-2 infection (Long COVID) in older adults

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Published

December 2024

Journal

GeroScience

Abstract

Long COVID, also known as PASC (post-acute sequelae of SARS-CoV-2), is a complex infection-associated chronic condition affecting tens of millions of people worldwide. Many aspects of this condition are incompletely understood. Among them is how this condition may manifest itself in older adults and how it might impact the older population. Here, we briefly review the current understanding of PASC in the adult population and examine what is known on its features with aging. Finally, we outline the major gaps and areas for research most germane to older adults.

Authors

Samantha J Russell, Karen Parker, Andrea Lehoczki, David Lieberman, Indu S Partha, Serena J Scott, Linda R Phillips, Mindy J Fain, Janko Ž Nikolich

Keywords

Clinical presentation; Long COVID; Molecular mechanisms; Older adults; SARS-CoV-2