Researchers within the RECOVER Initiative share their progress to understand, treat, and prevent Long COVID through research publications. Follow the latest science from RECOVER’s research studies below.
Visit the Research Summaries page to learn about RECOVER’s Long COVID research in a format that’s easy to understand.
Short SummaryRECOVER researchers used data in electronic health records (EHRs) from children’s hospitals that were a part of the National Pediatric Learning Health System Network (PEDSnet). Researchers looked for symptoms, health conditions, and medicines children had about 1 to 6 months after a COVID test. They compared children who did and didn’t have COVID to learn how many children who had COVID got Long COVID, and symptoms and health problems Long COVID causes in children.
The researchers learned that Long COVID is uncommon in children and happens in about 4% of children with COVID compared to in about 5% - 21% of adults with COVID. They also learned the Long COVID symptoms and health conditions that happen most often in children include changes in smell or taste hair loss, trouble breathing, and inflammation (swelling) in the heart or muscles.
Short SummaryRECOVER researchers wanted to learn if a computer program could identify if people have Long COVID based on electronic health records (EHRs). They used EHRs from the National COVID Cohort Collaborative (N3C). Researchers created and used a computer program to compare people with Long COVID to those who didn’t have Long COVID (based on whether or not people had a visit to a Long COVID clinic in their EHR). The computer program looked for patterns in people’s symptoms, health conditions, and other data.
The researchers concluded their computer program could be used to identify people with possible Long COVID. The computer program found that people with Long COVID have patterns in their health care visits, age groups, symptoms and health conditions, and the medicines they take. This could help connect people with Long COVID to health care or invite them to join research studies.
Short SummaryRECOVER researchers wanted to learn more about the chance of getting a mental health condition after having COVID. Researchers reviewed electronic health records (EHRs) of people who had COVID and people who had other types of respiratory tract infections (RTIs). They looked at how many people were diagnosed with a mental health condition shortly (21 days to 4 months) after having COVID compared to other RTIs. They also looked at how many people were diagnosed later (more than 4 months to 1 year) after having COVID compared to other RTIs.
The researchers found that people who had COVID were about a quarter (25%) more likely to be diagnosed with a mental health condition shortly after having COVID (21 days to 4 months afterwards) compared to people who had other RTIs. The researchers concluded that health care systems should do mental health screenings shortly after a person has COVID to better diagnose and treat mental health conditions.
Short SummaryRECOVER researchers used data from over 15 million people’s electronic health records (EHR) to compare how many people have heart problems after having COVID or getting an mRNA COVID vaccine. They used EHR data from 40 healthcare systems in PCORnet, the National Patient-Centered Clinical Research Network.
Researchers found that the chance of having heart problems is higher after having COVID than after getting an mRNA COVID vaccine for men and women in all age groups. The overall chance of having heart problems after having COVID or getting an mRNA COVID vaccine was very low across all ages and genders. These results support the continued use of mRNA COVID vaccines for all people who meet the vaccine criteria.
Short SummaryRECOVER researchers reviewed electronic health records (EHRs) of about 12 million adults and children who had a COVID test to look for new symptoms and health conditions that happened 1 to 5 months after the COVID test. They used EHR data from 40 healthcare systems in PCORnet, the National Patient-Centered Clinical Research Network. Researchers compared new symptoms and health conditions in adults and children who did and didn’t have COVID (tested positive or negative) and whether they were hospitalized with COVID.
Researchers found that having COVID raised the chance of adults and children getting new symptoms and health conditions, especially trouble breathing, unusual heart rates, and type 2 diabetes. The chance of getting some new symptoms and conditions went up if they were hospitalized with COVID.
